Mitochondrial concept of leukemogenesis: key role of oxygen-peroxide effects

BACKGROUND AND HYPOTHESIS: The high sensitivity of hematopoietic cells, especially stem cells, to radiation and to pro-oxidative and other leukemogenic agents is related to certain of their morphological and metabolic features. It is attributable to the low (minimal) number of active mitochondria an...

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Detalles Bibliográficos
Autores principales: Lyu, Boris N, Ismailov, Sanzhar B, Ismailov, Bolat, Lyu, Marina B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614412/
https://www.ncbi.nlm.nih.gov/pubmed/19014456
http://dx.doi.org/10.1186/1742-4682-5-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614412/
https://www.ncbi.nlm.nih.gov/pubmed/19014456
http://dx.doi.org/10.1186/1742-4682-5-23

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