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Mitochondrial concept of leukemogenesis: key role of oxygen-peroxide effects
BACKGROUND AND HYPOTHESIS: The high sensitivity of hematopoietic cells, especially stem cells, to radiation and to pro-oxidative and other leukemogenic agents is related to certain of their morphological and metabolic features. It is attributable to the low (minimal) number of active mitochondria an...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614412/ https://www.ncbi.nlm.nih.gov/pubmed/19014456 http://dx.doi.org/10.1186/1742-4682-5-23 |