Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells

BACKGROUND: A large percentage of patients with recurrent ovarian cancer develop resistance to the taxane class of chemotherapeutics. While mechanisms of resistance are being discovered, novel treatment options and a better understanding of disease resistance are sorely needed. The mitotic kinase Au...

Descripción completa

Detalles Bibliográficos
Autores principales: Scharer, Christopher D, Laycock, Noelani, Osunkoya, Adeboye O, Logani, Sanjay, McDonald, John F, Benigno, Benedict B, Moreno, Carlos S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614415/
https://www.ncbi.nlm.nih.gov/pubmed/19077237
http://dx.doi.org/10.1186/1479-5876-6-79

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614415/
https://www.ncbi.nlm.nih.gov/pubmed/19077237
http://dx.doi.org/10.1186/1479-5876-6-79

Ejemplares similares