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Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells

BACKGROUND: A large percentage of patients with recurrent ovarian cancer develop resistance to the taxane class of chemotherapeutics. While mechanisms of resistance are being discovered, novel treatment options and a better understanding of disease resistance are sorely needed. The mitotic kinase Au...

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Detalles Bibliográficos
Autores principales:	Scharer, Christopher D, Laycock, Noelani, Osunkoya, Adeboye O, Logani, Sanjay, McDonald, John F, Benigno, Benedict B, Moreno, Carlos S
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614415/ https://www.ncbi.nlm.nih.gov/pubmed/19077237 http://dx.doi.org/10.1186/1479-5876-6-79

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