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Genome stability is ensured by temporal control of kinetochore-microtubule dynamics
Most solid tumors are aneuploid and many frequently mis-segregate chromosomes. This chromosomal instability is commonly caused by persistent maloriented attachment of chromosomes to spindle microtubules. Chromosome segregation requires stable microtubule attachment at kinetochores, yet those attachm...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614462/ https://www.ncbi.nlm.nih.gov/pubmed/19060894 http://dx.doi.org/10.1038/ncb1809 |