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Poisson-Nernst-Planck Models of Nonequilibrium Ion Electrodiffusion through a Protegrin Transmembrane Pore

Protegrin peptides are potent antimicrobial agents believed to act against a variety of pathogens by forming nonselective transmembrane pores in the bacterial cell membrane. We have employed 3D Poisson-Nernst-Planck (PNP) calculations to determine the steady-state ion conduction characteristics of s...

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Detalles Bibliográficos
Autores principales: Bolintineanu, Dan S., Sayyed-Ahmad, Abdallah, Davis, H. Ted, Kaznessis, Yiannis N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614469/
https://www.ncbi.nlm.nih.gov/pubmed/19180178
http://dx.doi.org/10.1371/journal.pcbi.1000277