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Cell death upon epigenetic genome methylation: a novel function of methyl-specific deoxyribonucleases

BACKGROUND: Alteration in epigenetic methylation can affect gene expression and other processes. In Prokaryota, DNA methyltransferase genes frequently move between genomes and present a potential threat. A methyl-specific deoxyribonuclease, McrBC, of Escherichia coli cuts invading methylated DNAs. H...

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Detalles Bibliográficos
Autores principales: Fukuda, Eri, Kaminska, Katarzyna H, Bujnicki, Janusz M, Kobayashi, Ichizo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614495/
https://www.ncbi.nlm.nih.gov/pubmed/19025584
http://dx.doi.org/10.1186/gb-2008-9-11-r163