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A Novel and Critical Role for Oct4 as a Regulator of the Maternal-Embryonic Transition
BACKGROUND: Compared to the emerging embryonic stem cell (ESC) gene network, little is known about the dynamic gene network that directs reprogramming in the early embryo. We hypothesized that Oct4, an ESC pluripotency regulator that is also highly expressed at the 1- to 2-cell stages in embryos, ma...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2614881/ https://www.ncbi.nlm.nih.gov/pubmed/19129941 http://dx.doi.org/10.1371/journal.pone.0004109 |