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Gene expression deregulation by KRAS G12D and G12V in a BRAF V600E context

BACKGROUND: KRAS and BRAF mutations appear of relevance in the genesis and progression of several solid tumor types but the co-occurrence and interaction of these mutations have not yet been fully elucidated. Using a microsatellite stable (MSS) colorectal cancer (CRC) cell line (Colo741) having muta...

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Detalles Bibliográficos
Autores principales: Monticone, Massimiliano, Biollo, Emanuela, Maffei, Massimo, Donadini, Alessandra, Romeo, Francesco, Storlazzi, Clelia Tiziana, Giaretti, Walter, Castagnola, Patrizio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615043/
https://www.ncbi.nlm.nih.gov/pubmed/19087308
http://dx.doi.org/10.1186/1476-4598-7-92