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Integrase and integration: biochemical activities of HIV-1 integrase

Integration of retroviral DNA is an obligatory step of retrovirus replication because proviral DNA is the template for productive infection. Integrase, a retroviral enzyme, catalyses integration. The process of integration can be divided into two sequential reactions. The first one, named 3'-pr...

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Detalles Bibliográficos
Autores principales: Delelis, Olivier, Carayon, Kevin, Saïb, Ali, Deprez, Eric, Mouscadet, Jean-François
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615046/
https://www.ncbi.nlm.nih.gov/pubmed/19091057
http://dx.doi.org/10.1186/1742-4690-5-114