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Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum

To maintain protein homeostasis in secretory compartments, eukaryotic cells harbor a quality control system that monitors protein folding and protein complex assembly in the endoplasmic reticulum (ER). Proteins that do not fold properly or integrate into cognate complexes are degraded by ER-associat...

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Detalles Bibliográficos
Autores principales: Clerc, Simone, Hirsch, Christian, Oggier, Daniela Maria, Deprez, Paola, Jakob, Claude, Sommer, Thomas, Aebi, Markus
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615083/
https://www.ncbi.nlm.nih.gov/pubmed/19124653
http://dx.doi.org/10.1083/jcb.200809198