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Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulum
To maintain protein homeostasis in secretory compartments, eukaryotic cells harbor a quality control system that monitors protein folding and protein complex assembly in the endoplasmic reticulum (ER). Proteins that do not fold properly or integrate into cognate complexes are degraded by ER-associat...
Autores principales: | Clerc, Simone, Hirsch, Christian, Oggier, Daniela Maria, Deprez, Paola, Jakob, Claude, Sommer, Thomas, Aebi, Markus |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615083/ https://www.ncbi.nlm.nih.gov/pubmed/19124653 http://dx.doi.org/10.1083/jcb.200809198 |
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