Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity

Sonic hedgehog (Shh) is an indispensable, extrinsic cue that regulates progenitor and stem cell behavior in the developing and adult mammalian central nervous system. Here, we investigate the link between the Shh signaling pathway and Hes1, a classical Notch target. We show that Shh-driven stabiliza...

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Detalles Bibliográficos
Autores principales: Wall, Dana S., Mears, Alan J., McNeill, Brian, Mazerolle, Chantal, Thurig, Sherry, Wang, Yaping, Kageyama, Ryoichiro, Wallace, Valerie A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615087/
https://www.ncbi.nlm.nih.gov/pubmed/19124651
http://dx.doi.org/10.1083/jcb.200805155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615087/
https://www.ncbi.nlm.nih.gov/pubmed/19124651
http://dx.doi.org/10.1083/jcb.200805155

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