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Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity
Sonic hedgehog (Shh) is an indispensable, extrinsic cue that regulates progenitor and stem cell behavior in the developing and adult mammalian central nervous system. Here, we investigate the link between the Shh signaling pathway and Hes1, a classical Notch target. We show that Shh-driven stabiliza...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615087/ https://www.ncbi.nlm.nih.gov/pubmed/19124651 http://dx.doi.org/10.1083/jcb.200805155 |