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Sustained activation of STAT5 is essential for chromatin remodeling and maintenance of mammary-specific function

Epithelial cells, once dissociated and placed in two-dimensional (2D) cultures, rapidly lose tissue-specific functions. We showed previously that in addition to prolactin, signaling by laminin-111 was necessary to restore functional differentiation of mammary epithelia. Here, we elucidate two additi...

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Detalles Bibliográficos
Autores principales: Xu, Ren, Nelson, Celeste M., Muschler, John L., Veiseh, Mandana, Vonderhaar, Barbara K., Bissell, Mina J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615090/
https://www.ncbi.nlm.nih.gov/pubmed/19139262
http://dx.doi.org/10.1083/jcb.200807021