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Sustained activation of STAT5 is essential for chromatin remodeling and maintenance of mammary-specific function
Epithelial cells, once dissociated and placed in two-dimensional (2D) cultures, rapidly lose tissue-specific functions. We showed previously that in addition to prolactin, signaling by laminin-111 was necessary to restore functional differentiation of mammary epithelia. Here, we elucidate two additi...
Autores principales: | Xu, Ren, Nelson, Celeste M., Muschler, John L., Veiseh, Mandana, Vonderhaar, Barbara K., Bissell, Mina J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615090/ https://www.ncbi.nlm.nih.gov/pubmed/19139262 http://dx.doi.org/10.1083/jcb.200807021 |
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