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Regulation of diacylglycerol production and protein kinase C stimulation during sperm- and PLCζ-mediated mouse egg activation

Background information. At fertilization in mammalian eggs, the sperm induces a series of Ca(2+) oscillations via the production of inositol 1,4,5-trisphosphate. Increased inositol 1,4,5-trisphosphate production appears to be triggered by a sperm-derived PLCζ (phospholipase C-ζ) that enters the egg...

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Detalles Bibliográficos
Autores principales: Yu, Yuansong, Halet, Guillaume, Lai, F. Anthony, Swann, Karl
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615188/
https://www.ncbi.nlm.nih.gov/pubmed/18471090
http://dx.doi.org/10.1042/BC20080033