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Ablation of NMDA Receptors Enhances the Excitability of Hippocampal CA3 Neurons

Synchronized discharges in the hippocampal CA3 recurrent network are supposed to underlie network oscillations, memory formation and seizure generation. In the hippocampal CA3 network, NMDA receptors are abundant at the recurrent synapses but scarce at the mossy fiber synapses. We generated mutant m...

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Detalles Bibliográficos
Autores principales: Fukushima, Fumiaki, Nakao, Kazuhito, Shinoe, Toru, Fukaya, Masahiro, Muramatsu, Shin-ichi, Sakimura, Kenji, Kataoka, Hirotaka, Mori, Hisashi, Watanabe, Masahiko, Manabe, Toshiya, Mishina, Masayoshi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615205/
https://www.ncbi.nlm.nih.gov/pubmed/19142228
http://dx.doi.org/10.1371/journal.pone.0003993