Imaging of Viral Thymidine Kinase Gene Expression by Replicating Oncolytic Adenovirus and Prediction of Therapeutic Efficacy

PURPOSE: We have used a genetically attenuated adenoviral vector which expresses HSVtk to assess the possible additive role of suicidal gene therapy for enhanced oncolytic effect of the virus. Expression of TK was measured using a radiotracer-based molecular counting and imaging system. MATERIALS AN...

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Detalles Bibliográficos
Autores principales: Kim, Eun-Jung, Yoo, Ji Young, Choi, Young-Hwan, Ahn, Keun-Jae, Lee, Jong-Doo, Yun, Chae-Ok, Yun, Mijin
Formato: Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2008
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615367/
https://www.ncbi.nlm.nih.gov/pubmed/18972602
http://dx.doi.org/10.3349/ymj.2008.49.5.811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615367/
https://www.ncbi.nlm.nih.gov/pubmed/18972602
http://dx.doi.org/10.3349/ymj.2008.49.5.811

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