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Long-Term Vector Integration Site Analysis Following Retroviral Mediated Gene Transfer to Hematopoietic Stem Cells for the Treatment of HIV Infection

We previously reported the efficacy of nonmyeloablative allogeneic transplantation in 2 HIV positive recipients, one of whom received retrovirus transduced hematopoietic stem cells to confer resistance to HIV. Here we report an assessment of retroviral integration sites (RISs) recovered out to 3 yea...

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Detalles Bibliográficos
Autores principales: Hayakawa, Jun, Washington, Kareem, Uchida, Naoya, Phang, Oswald, Kang, Elizabeth M., Hsieh, Matthew M., Tisdale, John F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615408/
https://www.ncbi.nlm.nih.gov/pubmed/19148292
http://dx.doi.org/10.1371/journal.pone.0004211