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Norrin attenuates protease-mediated death of transformed retinal ganglion cells

PURPOSE: To investigate the effects of norrin, a nonconventional ligand for Wingless-Int (Wnt)-beta-catenin signaling pathway, on protease-mediated death of transformed rat retinal ganglion cells (RGC-5). METHODS: Transformed RGC-5 cells were treated with 2.0 μM staurosporine (SS), a broad-spectrum...

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Detalles Bibliográficos
Autores principales: Lin, Song, Cheng, Mei, Dailey, Wendelin, Drenser, Kimberly, Chintala, Shravan
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615462/
https://www.ncbi.nlm.nih.gov/pubmed/19137075