Cargando…
Norrin attenuates protease-mediated death of transformed retinal ganglion cells
PURPOSE: To investigate the effects of norrin, a nonconventional ligand for Wingless-Int (Wnt)-beta-catenin signaling pathway, on protease-mediated death of transformed rat retinal ganglion cells (RGC-5). METHODS: Transformed RGC-5 cells were treated with 2.0 μM staurosporine (SS), a broad-spectrum...
Autores principales: | Lin, Song, Cheng, Mei, Dailey, Wendelin, Drenser, Kimberly, Chintala, Shravan |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615462/ https://www.ncbi.nlm.nih.gov/pubmed/19137075 |
Ejemplares similares
-
Inhibition of Reactive Gliosis Attenuates Excitotoxicity-Mediated Death of Retinal Ganglion Cells
por: Ganesh, Bhagyalaxmi S., et al.
Publicado: (2011) -
Norrin Protects Retinal Ganglion Cells from Excitotoxic Damage via the Induction of Leukemia Inhibitory Factor
por: Kassumeh, Stefan, et al.
Publicado: (2020) -
Decreased Expression of DREAM Promotes the Degeneration of Retinal Neurons
por: Chintala, Shravan, et al.
Publicado: (2015) -
Wnt signaling pathway in retinal vascularization
por: Drenser, Kimberly A
Publicado: (2016) -
Norrin-induced Frizzled4 endocytosis and endo-lysosomal trafficking control retinal angiogenesis and barrier function
por: Zhang, Chi, et al.
Publicado: (2017)