Comprehensive analysis of T cell epitope discovery strategies using 17DD yellow fever virus structural proteins and BALB/c (H2(d)) mice model

Immunomics research uses in silico epitope prediction, as well as in vivo and in vitro approaches. We inoculated BALB/c (H2(d)) mice with 17DD yellow fever vaccine to investigate the correlations between approaches used for epitope discovery: ELISPOT assays, binding assays, and prediction software....

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Detalles Bibliográficos
Autores principales: Maciel, Milton, Kellathur, Srinivasan N., Chikhlikar, Pryia, Dhalia, Rafael, Sidney, John, Sette, Alessandro, August, Thomas J., Marques, Ernesto T.A.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Inc. Published by Elsevier Inc. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615555/
https://www.ncbi.nlm.nih.gov/pubmed/18579176
http://dx.doi.org/10.1016/j.virol.2008.04.043