Minor changes largely restore catalytic activity of archaeal RNase P RNA from Methanothermobacter thermoautotrophicus

The increased protein proportion of archaeal and eukaryal ribonuclease (RNase) P holoenzymes parallels a vast decrease in the catalytic activity of their RNA subunits (P RNAs) alone. We show that a few mutations toward the bacterial P RNA consensus substantially activate the catalytic (C-) domain of...

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Detalles Bibliográficos
Autores principales: Li, Dan, Willkomm, Dagmar K., Hartmann, Roland K.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615603/
https://www.ncbi.nlm.nih.gov/pubmed/19036794
http://dx.doi.org/10.1093/nar/gkn915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615603/
https://www.ncbi.nlm.nih.gov/pubmed/19036794
http://dx.doi.org/10.1093/nar/gkn915

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