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A single molecule array for digital targeted molecular analyses

We present a new random array format together with a decoding scheme for targeted multiplex digital molecular analyses. DNA samples are analyzed using multiplex sets of padlock or selector probes that create circular DNA molecules upon target recognition. The circularized DNA molecules are amplified...

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Detalles Bibliográficos
Autores principales: Göransson, Jenny, Wählby, Carolina, Isaksson, Magnus, Howell, W. Mathias, Jarvius, Jonas, Nilsson, Mats
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615615/
https://www.ncbi.nlm.nih.gov/pubmed/19033366
http://dx.doi.org/10.1093/nar/gkn921