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Identification of a signature motif in target mRNAs of RNA-binding protein AUF1

The ubiquitous RNA-binding protein AUF1 promotes the degradation of some target mRNAs, but increases the stability and translation of other targets. Here, we isolated AUF1-associated mRNAs by immunoprecipitation of (AUF1–RNA) ribonucleoprotein (RNP) complexes from HeLa cells, identified them using m...

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Detalles Bibliográficos
Autores principales: Mazan-Mamczarz, Krystyna, Kuwano, Yuki, Zhan, Ming, White, Elizabeth J., Martindale, Jennifer L., Lal, Ashish, Gorospe, Myriam
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615618/
https://www.ncbi.nlm.nih.gov/pubmed/19033365
http://dx.doi.org/10.1093/nar/gkn929