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Role of cAMP in the promotion of colorectal cancer cell growth by Prostaglandin E2

BACKGROUND: Prostaglandin E2 (PGE2), a product of the cyclooxygenase (COX) reaction, stimulates the growth of colonic epithelial cells. It is inferred that the abrogation of prostaglandins' growth-promoting effects as a result of COX inhibition underlies the advantageous effects of non-steroida...

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Detalles Bibliográficos
Autores principales: Löffler, Ivonne, Grün, Michael, Böhmer, Frank D, Rubio, Ignacio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615781/
https://www.ncbi.nlm.nih.gov/pubmed/19099561
http://dx.doi.org/10.1186/1471-2407-8-380