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Host HLA B*Allele-Associated Multi-Clade Gag T-Cell Recognition Correlates with Slow HIV-1 Disease Progression in Antiretroviral Therapy-Naïve Ugandans

BACKGROUND: Some HIV infected individuals remain asymptomatic for protracted periods of time in the absence of antiretroviral therapy (ART). Virological control, CD4 T cell loss and HIV-specific responses are some of the key interrelated determinants of HIV-1 disease progression. In this study, poss...

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Detalles Bibliográficos
Autores principales: Serwanga, Jennifer, Shafer, Leigh Anne, Pimego, Edward, Auma, Betty, Watera, Christine, Rowland, Samantha, Yirrell, David, Pala, Pietro, Grosskurth, Heiner, Whitworth, Jimmy, Gotch, Frances, Kaleebu, Pontiano
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2617765/
https://www.ncbi.nlm.nih.gov/pubmed/19142234
http://dx.doi.org/10.1371/journal.pone.0004188