TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity

The role of various p73 isoforms in tumorigenesis has been controversial. However, as we have recently shown, the generation of TAp73-deficient (TAp73(−/−)) mice reveals that TAp73 isoforms exert tumor-suppressive functions, indicating an emerging role for Trp-73 in the maintenance of genomic stabil...

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Detalles Bibliográficos
Autores principales: Tomasini, Richard, Tsuchihara, Katsuya, Tsuda, Chiharu, Lau, Suzanne K., Wilhelm, Margareta, Rufini, Alessandro, Tsao, Ming-sound, Iovanna, Juan L., Jurisicova, Andrea, Melino, Gerry, Mak, Tak W.
Formato: Texto
Lenguaje:English
Publicado: National Academy of Sciences 2009
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621249/
https://www.ncbi.nlm.nih.gov/pubmed/19139399
http://dx.doi.org/10.1073/pnas.0812096106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621249/
https://www.ncbi.nlm.nih.gov/pubmed/19139399
http://dx.doi.org/10.1073/pnas.0812096106

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