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TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity
The role of various p73 isoforms in tumorigenesis has been controversial. However, as we have recently shown, the generation of TAp73-deficient (TAp73(−/−)) mice reveals that TAp73 isoforms exert tumor-suppressive functions, indicating an emerging role for Trp-73 in the maintenance of genomic stabil...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621249/ https://www.ncbi.nlm.nih.gov/pubmed/19139399 http://dx.doi.org/10.1073/pnas.0812096106 |