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Inflammatory Genital Infections Mitigate a Severe Genetic Bottleneck in Heterosexual Transmission of Subtype A and C HIV-1

The HIV-1 epidemic in sub-Saharan Africa is driven largely by heterosexual transmission of non-subtype B viruses, of which subtypes C and A are predominant. Previous studies of subtype B and subtype C transmission pairs have suggested that a single variant from the chronically infected partner can e...

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Detalles Bibliográficos
Autores principales: Haaland, Richard E., Hawkins, Paulina A., Salazar-Gonzalez, Jesus, Johnson, Amber, Tichacek, Amanda, Karita, Etienne, Manigart, Olivier, Mulenga, Joseph, Keele, Brandon F., Shaw, George M., Hahn, Beatrice H., Allen, Susan A., Derdeyn, Cynthia A., Hunter, Eric
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621345/
https://www.ncbi.nlm.nih.gov/pubmed/19165325
http://dx.doi.org/10.1371/journal.ppat.1000274