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The Importance of pH in Regulating the Function of the Fasciola hepatica Cathepsin L1 Cysteine Protease

The helminth parasite Fasciola hepatica secretes cathepsin L cysteine proteases to invade its host, migrate through tissues and digest haemoglobin, its main source of amino acids. Here we investigated the importance of pH in regulating the activity and functions of the major cathepsin L protease Fhe...

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Detalles Bibliográficos
Autores principales: Lowther, Jonathan, Robinson, Mark W., Donnelly, Sheila M., Xu, Weibo, Stack, Colin M., Matthews, Jacqueline M., Dalton, John P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621350/
https://www.ncbi.nlm.nih.gov/pubmed/19172172
http://dx.doi.org/10.1371/journal.pntd.0000369