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What Does PLIER Really Do?

MOTIVATION: Our goal was to understand why the PLIER algorithm performs so well given its derivation is based on a biologically implausible assumption. RESULTS: In spite of a non-intuitive assumption regarding the PM and MM errors made as part of the derivation for PLIER, the resulting probe level e...

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Detalles Bibliográficos
Autores principales: Therneau, Terry M., Ballman, Karla V.
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2623311/
https://www.ncbi.nlm.nih.gov/pubmed/19259420