Long-term actions of interleukin-1β on delay and tonic firing neurons in rat superficial dorsal horn and their relevance to central sensitization

BACKGROUND: Cytokines such as interleukin 1β (IL-1β) have been implicated in the development of central sensitization that is characteristic of neuropathic pain. To examine its long-term effect on nociceptive processing, defined medium organotypic cultures of rat spinal cord were exposed to 100 pM I...

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Detalles Bibliográficos
Autores principales: Gustafson-Vickers, Sabrina L, Lu, Van B, Lai, Aaron Y, Todd, Kathryn G, Ballanyi, Klaus, Smith, Peter A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2625335/
https://www.ncbi.nlm.nih.gov/pubmed/19091115
http://dx.doi.org/10.1186/1744-8069-4-63

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2625335/
https://www.ncbi.nlm.nih.gov/pubmed/19091115
http://dx.doi.org/10.1186/1744-8069-4-63

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