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Mycobacterium tuberculosis Rv3802c Encodes a Phospholipase/Thioesterase and Is Inhibited by the Antimycobacterial Agent Tetrahydrolipstatin

The cell wall of M. tuberculosis is central to its success as a pathogen. Mycolic acids are key components of this cell wall. The genes involved in joining the α and mero mycolates are located in a cluster, beginning with Rv3799c and extending at least until Rv3804c. The role of each enzyme encoded...

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Detalles Bibliográficos
Autores principales: Parker, Sarah K., Barkley, Robert M., Rino, John G., Vasil, Michael L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2625445/
https://www.ncbi.nlm.nih.gov/pubmed/19169353
http://dx.doi.org/10.1371/journal.pone.0004281