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Sensitive and Specific Detection of the Non-Human Sialic Acid N-Glycolylneuraminic Acid In Human Tissues and Biotherapeutic Products

BACKGROUND: Humans are genetically defective in synthesizing the common mammalian sialic acid N-glycolylneuraminic acid (Neu5Gc), but can metabolically incorporate it from dietary sources (particularly red meat and milk) into glycoproteins and glycolipids of human tumors, fetuses and some normal tis...

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Detalles Bibliográficos
Autores principales: Diaz, Sandra L., Padler-Karavani, Vered, Ghaderi, Darius, Hurtado-Ziola, Nancy, Yu, Hai, Chen, Xi, Brinkman-Van der Linden, Els C. M., Varki, Ajit, Varki, Nissi M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626223/
https://www.ncbi.nlm.nih.gov/pubmed/19156207
http://dx.doi.org/10.1371/journal.pone.0004241