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Proteomic-Based Detection of a Protein Cluster Dysregulated during Cardiovascular Development Identifies Biomarkers of Congenital Heart Defects

BACKGROUND: Cardiovascular development is vital for embryonic survival and growth. Early gestation embryo loss or malformation has been linked to yolk sac vasculopathy and congenital heart defects (CHDs). However, the molecular pathways that underlie these structural defects in humans remain largely...

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Detalles Bibliográficos
Autores principales: Nath, Anjali K., Krauthammer, Michael, Li, Puyao, Davidov, Eugene, Butler, Lucas C., Copel, Joshua, Katajamaa, Mikko, Oresic, Matej, Buhimschi, Irina, Buhimschi, Catalin, Snyder, Michael, Madri, Joseph A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626248/
https://www.ncbi.nlm.nih.gov/pubmed/19156209
http://dx.doi.org/10.1371/journal.pone.0004221