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Abeta42-Induced Neurodegeneration via an Age-Dependent Autophagic-Lysosomal Injury in Drosophila
The mechanism of widespread neuronal death occurring in Alzheimer's disease (AD) remains enigmatic even after extensive investigation during the last two decades. Amyloid beta 42 peptide (Aβ(1–42)) is believed to play a causative role in the development of AD. Here we expressed human Aβ(1–42) a...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626277/ https://www.ncbi.nlm.nih.gov/pubmed/19145255 http://dx.doi.org/10.1371/journal.pone.0004201 |