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Abeta42-Induced Neurodegeneration via an Age-Dependent Autophagic-Lysosomal Injury in Drosophila

The mechanism of widespread neuronal death occurring in Alzheimer's disease (AD) remains enigmatic even after extensive investigation during the last two decades. Amyloid beta 42 peptide (Aβ(1–42)) is believed to play a causative role in the development of AD. Here we expressed human Aβ(1–42) a...

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Detalles Bibliográficos
Autores principales:	Ling, Daijun, Song, Ho-Juhn, Garza, Dan, Neufeld, Thomas P., Salvaterra, Paul M.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626277/ https://www.ncbi.nlm.nih.gov/pubmed/19145255 http://dx.doi.org/10.1371/journal.pone.0004201

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