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Does the pain-protective GTP cyclohydrolase haplotype significantly alter the pattern or severity of pain in humans with chronic pancreatitis?

BACKGROUND: Pain is often a dominant clinical feature of chronic pancreatitis but the frequency and severity is highly variable between subjects. We hypothesized that genetic polymorphisms contribute to variations in clinical pain patterns. Since genetic variations in the GTP cyclohydrolase (GCH1) g...

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Detalles Bibliográficos
Autores principales: Lazarev, Mark, Lamb, Janette, Barmada, M Michael, Dai, Feng, Anderson, Michelle A, Max, Mitchell B, Whitcomb, David C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626574/
https://www.ncbi.nlm.nih.gov/pubmed/19014702
http://dx.doi.org/10.1186/1744-8069-4-58