Cargando…

SIRT1 genetic variants associate with the metabolic response of Caucasians to a controlled lifestyle intervention – the TULIP Study

BACKGROUND: Sirtuin1 (SIRT1) regulates gene expression in distinct metabolic pathways and mediates beneficial effects of caloric restriction in animal models. In humans, SIRT1 genetic variants associate with fasting energy expenditure. To investigate the relevance of SIRT1 for human metabolism and c...

Descripción completa

Detalles Bibliográficos
Autores principales: Weyrich, Peter, Machicao, Fausto, Reinhardt, Julia, Machann, Jürgen, Schick, Fritz, Tschritter, Otto, Stefan, Norbert, Fritsche, Andreas, Häring, Hans-Ulrich
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626584/
https://www.ncbi.nlm.nih.gov/pubmed/19014491
http://dx.doi.org/10.1186/1471-2350-9-100