Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition

Human leukocyte antigen (HLA) gene polymorphism plays a critical role in protective immunity, disease susceptibility, autoimmunity, and drug hypersensitivity, yet the basis of how HLA polymorphism influences T cell receptor (TCR) recognition is unclear. We examined how a natural micropolymorphism in...

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Detalles Bibliográficos
Autores principales: Archbold, Julia K., Macdonald, Whitney A., Gras, Stephanie, Ely, Lauren K., Miles, John J., Bell, Melissa J., Brennan, Rebekah M., Beddoe, Travis, Wilce, Matthew C.J., Clements, Craig S., Purcell, Anthony W., McCluskey, James, Burrows, Scott R., Rossjohn, Jamie
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626662/
https://www.ncbi.nlm.nih.gov/pubmed/19139173
http://dx.doi.org/10.1084/jem.20082136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626662/
https://www.ncbi.nlm.nih.gov/pubmed/19139173
http://dx.doi.org/10.1084/jem.20082136

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