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Estrogen directly activates AID transcription and function

The immunological targets of estrogen at the molecular, humoral, and cellular level have been well documented, as has estrogen's role in establishing a gender bias in autoimmunity and cancer. During a healthy immune response, activation-induced deaminase (AID) deaminates cytosines at immunoglob...

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Detalles Bibliográficos
Autores principales: Pauklin, Siim, Sernández, Isora V., Bachmann, Gudrun, Ramiro, Almudena R., Petersen-Mahrt, Svend K.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626679/
https://www.ncbi.nlm.nih.gov/pubmed/19139166
http://dx.doi.org/10.1084/jem.20080521