Cargando…

Direct observations of the kinetics of migrating T cells suggest active retention by endothelial cells with continual bidirectional migration

The kinetics and regulatory mechanisms of T cell migration through the endothelium have not been fully defined. In experimental, filter-based assays in vitro, transmigration of lymphocytes takes hours, compared with minutes, in vivo. We cultured endothelial cell (EC) monolayers on filters, solid sub...

Descripción completa

Detalles Bibliográficos
Autores principales: McGettrick, Helen M., Hunter, Kirsty, Moss, Paul A., Buckley, Christopher D., Rainger, G. Ed, Nash, Gerard B.
Formato: Texto
Lenguaje:English
Publicado: The Society for Leukocyte Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626767/
https://www.ncbi.nlm.nih.gov/pubmed/18948550
http://dx.doi.org/10.1189/jlb.0508301