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Fibril Growth Kinetics Reveal a Region of β(2)-microglobulin Important for Nucleation and Elongation of Aggregation
Amyloid is a highly ordered form of aggregate comprising long, straight and unbranched proteinaceous fibrils that are formed with characteristic nucleation-dependent kinetics in vitro. Currently, the structural molecular mechanism of fibril nucleation and elongation is poorly understood. Here, we in...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627305/ https://www.ncbi.nlm.nih.gov/pubmed/18342332 http://dx.doi.org/10.1016/j.jmb.2008.01.092 |