Human Cord Blood Stem Cell-Modulated Regulatory T Lymphocytes Reverse the Autoimmune-Caused Type 1 Diabetes in Nonobese Diabetic (NOD) Mice

BACKGROUND: The deficit of pancreatic islet β cells caused by autoimmune destruction is a crucial issue in type 1 diabetes (T1D). It is essential to fundamentally control the autoimmunity for treatment of T1D. Regulatory T cells (Tregs) play a pivotal role in maintaining self-tolerance through their...

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Detalles Bibliográficos
Autores principales: Zhao, Yong, Lin, Brian, Darflinger, Robert, Zhang, Yongkang, Holterman, Mark J., Skidgel, Randal A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627485/
https://www.ncbi.nlm.nih.gov/pubmed/19156219
http://dx.doi.org/10.1371/journal.pone.0004226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627485/
https://www.ncbi.nlm.nih.gov/pubmed/19156219
http://dx.doi.org/10.1371/journal.pone.0004226

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