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Human Cord Blood Stem Cell-Modulated Regulatory T Lymphocytes Reverse the Autoimmune-Caused Type 1 Diabetes in Nonobese Diabetic (NOD) Mice
BACKGROUND: The deficit of pancreatic islet β cells caused by autoimmune destruction is a crucial issue in type 1 diabetes (T1D). It is essential to fundamentally control the autoimmunity for treatment of T1D. Regulatory T cells (Tregs) play a pivotal role in maintaining self-tolerance through their...
Autores principales: | Zhao, Yong, Lin, Brian, Darflinger, Robert, Zhang, Yongkang, Holterman, Mark J., Skidgel, Randal A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627485/ https://www.ncbi.nlm.nih.gov/pubmed/19156219 http://dx.doi.org/10.1371/journal.pone.0004226 |
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