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Differential Activity of Caspase-3 Regulates Susceptibility of Lung and Breast Tumor Cell Lines to Paclitaxel

Recent development of tumor resistance to paclitaxel presents a major problem to cancer treatment. An unsettled controversy in the cancer chemotherapy field, however, is whether caspases play a prominent role in paclitaxel-induced death in tumors. Previous studies suggest that cleavage of caspase-3...

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Detalles Bibliográficos
Autores principales: Odonkor, Charles Amoatey, Achilefu, Samuel
Formato: Texto
Lenguaje:English
Publicado: Bentham Open 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627519/
https://www.ncbi.nlm.nih.gov/pubmed/19238186
http://dx.doi.org/10.2174/1874091X00802010121