Rhythmicity in Mice Selected for Extremes in Stress Reactivity: Behavioural, Endocrine and Sleep Changes Resembling Endophenotypes of Major Depression

BACKGROUND: Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis, including hyper- or hypo-activity of the stress hormone system, plays a critical role in the pathophysiology of mood disorders such as major depression (MD). Further biological hallmarks of MD are disturbances in circadian r...

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Detalles Bibliográficos
Autores principales: Touma, Chadi, Fenzl, Thomas, Ruschel, Jörg, Palme, Rupert, Holsboer, Florian, Kimura, Mayumi, Landgraf, Rainer
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627900/
https://www.ncbi.nlm.nih.gov/pubmed/19177162
http://dx.doi.org/10.1371/journal.pone.0004325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627900/
https://www.ncbi.nlm.nih.gov/pubmed/19177162
http://dx.doi.org/10.1371/journal.pone.0004325

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