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The Ubiquitin Ligase RPM-1 and the p38 MAPK PMK-3 Regulate AMPA Receptor Trafficking

Ubiquitination occurs at synapses, yet its role remains unclear. Previous studies demonstrated that the RPM-1 ubiquitin ligase organizes presynaptic boutons at neuromuscular junctions in C. elegans motorneurons. Here we find that RPM-1 has a novel postsynaptic role in interneurons, where it regulate...

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Detalles Bibliográficos
Autores principales: Park, Eun Chan, Glodowski, Doreen R., Rongo, Christopher
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627918/
https://www.ncbi.nlm.nih.gov/pubmed/19172179
http://dx.doi.org/10.1371/journal.pone.0004284